Recombinant Rat M-CSF/CSF1

Recombinant Rat M-CSF/CSF1

SKU: C470-10ug
Recombinant Rat Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Gln33-Arg254 is expressed. Bon Opus Cat. #C470
  • Accession Number

  • Background

    Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
  • Expression

    Human Cells
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
  • ALTnames

    Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1

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