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Recombinant Rat B7-2/CD86 (C-6His)
Recombinant Rat T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CP43

Recombinant Rat B7-2/CD86 (C-6His)

SKU: CP43-10ug
$79.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O35531
Species
Rat
Expression System
Human Cells
Target Sequence
Vla29-Lys247
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86
Alternative Names
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Citation
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Activity
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