Recombinant Rat 5'-Nucleotidase/CD73 (C-6His)
Recombinant Rat 5'-Nucleotidase/CD73 is produced by our expression system and the target gene encoding Trp29-Lys549 is expressed Bon Opus Cat. #CB16
BackgroundCD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesCD73; E5NT;Nucleotidase; NT5E;ecto-5'-nucleotidase