Recombinant Mouse Tyrosine Protein Kinase Receptor TYRO3 is produced by our Mammalian expression system and the target gene encoding Ala31-Ser418 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CK68

Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3/DTK (C-Fc)

Name: Recombinant Mouse Tyrosine-Protein Kinase Receptor TYRO3/DTK (C-Fc)
SKU: CK68-10ug

SKU: CK68-10ug

$32.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P55144

Species

Mouse

Expression System

Human Cells

Target Sequence

Ala31-Ser418

C-Fc

Formulation

Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.

Packaging

Ambient

Background

Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.