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Recombinant Mouse Thrombomodulin/BDCA-3/CD141 (C-6His)
Recombinant Mouse Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Leu17-Ser517 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CU09

Recombinant Mouse Thrombomodulin/BDCA-3/CD141 (C-6His)

SKU: CU09-10ug
$158.00Price
Quantity
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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

Please contact us to order for  international shipments.

Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P15306
Species
Mouse
Expression System
Human Cells
Target Sequence
Leu17-Ser517
Tag
C-His
Formulation
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0
.
Packaging
Dry Ice/ice packs
Background
Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). In addition, THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Thrombomodulin; TM; Fetomodulin; CD141; BDCA-3; Thbd
Alternative Names
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Citation
NA
Activity
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