Recombinant Mouse Macrophage Receptor MARCO/MARCO (N-8His)
SKU: CU63-10ug
$80.00Price
Recombinant Mouse Macrophage Receptor MARCO is produced by our Mammalian expression system and the target gene encoding Gln70-Ser518 is expressed with a 8His tag at the N-terminus. Bon Opus Cat. #CU63
Size
Accession Number
Q60754Background
MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellular domain (ECD) that includes a stalk region, a collagenlike region, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and other determinants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.Expression
Human CellsPackaging
AmbientFormulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.ALTnames
Macrophage receptor MARCO; Marco; Macrophage receptor with collagenous structure