Recombinant Mouse Interleukin-22/IL-22 (C-mFc)

Recombinant Mouse Interleukin-22/IL-22 (C-mFc)

SKU: CM71-10ug
$105.00Price
Recombinant Mouse Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Leu34-Val179 is expressed with a mFc tag at the C-terminus. Bon Opus Cat. #CM71
Size
  • Accession Number

    Q9JJY9
  • Background

    Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
  • Expression

    Human Cells
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
  • ALTnames

    Interleukin-22, IL-22, IL-TIF alpha, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, Interleukin-22a, IL-22a
Blue%20DNA%20(stock%20photo)_edited.jpg
  • Twitter
  • Facebook
  • LinkedIn

Terms and Conditions  I  Privacy Policy  I  Legal  I  Sitemap ©2020 by Bon Opus Biosciences, LLC.     150 Essex St, Millburn, NJ 07041, USA