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Recombinant Mouse HVEM/TNFRSF14/TR2/CD270 (C-Fc)
Recombinant Mouse Herpesvirus Entry Mediator is produced by our Mammalian expression system and the target gene encoding Gln39-Val207 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CJ90

Recombinant Mouse HVEM/TNFRSF14/TR2/CD270 (C-Fc)

SKU: CJ90-10ug
$53.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
Q80WM9
Species
Mouse
Expression System
Human Cells
Target Sequence
Gln39-Val207
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. It has demonstrated that HVEM Ig is able to exert a significant antiviral effect against HSV-1 infection in vivo.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Tnfrsf14; Herpesvirus entry mediator;HVEM; TR2;TNF receptor-like molecule;ATAR;another TRAF-associated receptor;Tumor necrosis factor receptor superfamily member 14
Alternative Names
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Citation
Immobilized Mouse HVEM-Fc(Cat#CJ90) at 6μg/ml (100 μl/well) can bind Human BTLA-His (Cat#C563).
Activity
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