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Recombinant Mouse Cathepsin S/CTSS (C-6His)

SKU: CM37-10ug
$150.00Price
Recombinant Mouse Cathepsin S is produced by our Mammalian expression system and the target gene encoding Val18-Ile340 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CM37
Size
  • Accession Number

    O70370
  • Background

    Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer’s disease (AD) and Down Syndrome (DS).
  • Expression

    Human Cells
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
  • ALTnames

    Cathepsin S, CTSS