Recombinant Mouse Cathepsin D/CSTD (C-6His)

Recombinant Mouse Cathepsin D/CSTD (C-6His)

SKU: CC21-10ug
Recombinant Mouse Cathepsin D is produced by our Mammalian expression system and the target gene encoding Ile21-Leu410 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CC21
  • Accession Number

  • Background

    CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.
  • Expression

    Human Cells
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM MES,150mM NaCl,pH5.5.
  • ALTnames

    Cathepsin D, CTSD,CPSD
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