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Recombinant Mouse Cadherin-3/P-Cadherin/CDH3 (C-Fc)

Recombinant Mouse Cadherin-3/P-Cadherin/CDH3 (C-Fc)

SKU: CK97-10ug
$79.00Price
Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CK97
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P10287
Species
Mouse
Expression System
Human Cells
Target Sequence
Glu100-Gly647
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Cadherin-3; Placental cadherin; P-cadherin; Cdh3
Alternative Names
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Citation
NA
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