Recombinant Mouse C-C motif Chemokine 8 is produced by our expression system and the target gene encoding Glu20-Pro97 is expressed Bon Opus Cat. #CS45
Recombinant Mouse C-C motif Chemokine 8/CCL8/MCP-2 (C-6His)
SKU: CS45-10ug
$158.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
Q9Z121
Species
Mouse
Expression System
Human Cells
Target Sequence
Glu20-Pro97
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM Hac-NaC, 150mM NaCl, pH4.0.
Packaging
Ambient
Background
Chemokine ligand 8 (CCL8,MCP-2), is a small secreted cytokine which belongs to the intercrine beta (chemokine CC) family. CCL8 Chemotactic factor attracts monocytes. It can bind heparin.CCL8 functions to activate different immune cells, including mast cells, eosinophils and basophils which are involved in allergic responses, monocytes, and T cells and NK cells which are involved in the inflammatory response. Its ability achieves by binding to different cell surface receptors termed chemokine receptors including CCR1, CCR2B and CCR5. It has been reported that CCL8 is a potent inhibitor of HIV-1 by virtue of its binding to CCR5 which is one of the major co-receptors for HIV-1.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
C-C motif chemokine 8;Ccl8;Monocyte chemoattractant protein 2;Monocyte chemotactic protein 2;MCP-2;Small-inducible cytokine A8;Mcp2; Scya8
Alternative Names
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Citation
NA
Activity
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