Recombinant Mouse Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Trp247 is expressed fused with a 6His tag at the C-terminus. Bon Opus Cat. #CS10

Recombinant Mouse Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-6His)

Name: Recombinant Mouse Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-6His)
SKU: CS10-10ug

SKU: CS10-10ug

$100.00

Quantity

[{"key":"CS10-10ug","value":"Backorder"},{"key":"CS10-500ug","value":"Backorder"},{"key":"CS10-1mg","value":"Backorder"},{"key":"CS10-50ug","value":"Backorder"}]

FAQ

Contact Us

Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

Distributors

Have Other Questions?

Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

Datasheet not available? Submit a request here

Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

Q62556

Species

Mouse

Expression System

Human Cells

Target Sequence

Ala27-Trp247

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mMNaCl, pH7.4.

Packaging

Ambient

Background

Mouse Butyrophilin subfamily 1 member A1(BTN1A1) is a type I transmembrane glycoprotein which is a member of the Ig superfamily. The BTN1A1 ECD displays two predicted IgV and IgC domains as do B7 and Skint proteins which interact with other Ig superfamily members. BTN1A1 binds to xanthine oxidoreductase (XOR). This interaction stabilizes the association of XOR with the milk fat globule membrane and appears to be essential in the control of milk fat globule secretion. In vitro, BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL-2 and IFN-γ secretion. Furthermore, in vivo, BTN1A1 has a protective effect against the development of experimental autoimmune encephalomyelitis (EAE). Because butyrophilins are structurally related to B7 proteins and are functionally implicated in immune regulation, they may represent an emerging family of costimulatory/inhibitory molecules.