Recombinant Mouse Bone Sialoprotein 2/IBSP (C-6His)
Recombinant Mouse Bone Sialoprotein 2 is produced by our Mammalian expression system and the target gene encoding Phe17-Gln324 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CB55
BackgroundIBSP, is a monomeric non-collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N-terminus (aa 17-62), a central region (aa 63-233), and an acidic C-terminus (aa 234-317). IBSP is highly glycosylated, sulfated and phosphorylated. Phosphorylation promotes HAp nucleation, while carbohydrate may regulate cell adhesion.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
ALTnamesBNSP; Bone sialoprotein 2; Bone sialoprotein; BSP; BSP2; BSPII; Cell binding sialoprotein; IBSP; Integrin binding sialoprotein; SP II;