BackgroundAnterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM Tris,10%Glycerol,100mM NaCl,pH8.0.
ALTnamesAnterior gradient protein 3; AGR3;AG3;BCMP11