Recombinant Mouse ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1 is produced by our Mammalian expression system and the target gene encoding Leu45-Thr304 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CU98

Recombinant Mouse ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1/CD38 (C-Fc)

Name: Recombinant Mouse ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1/CD38 (C-Fc)
SKU: CU98-10ug

SKU: CU98-10ug

$53.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

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Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P56528

Species

Mouse

Expression System

Human Cells

Target Sequence

Leu45-Thr304

C-Fc

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Packaging

Ambient

Background

CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.