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Recombinant Mouse beta-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Met130-Arg239 is expressed. Bon Opus Cat. #C793

Recombinant Mouse β-Nerve Growth Factor/β-NGF (Met130-Arg239)

SKU: C793-10ug
$53.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P01139
Species
Mouse
Expression System
E.coli
Target Sequence
Met130-Arg239
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB,200mM NaCl,pH8.0.
Packaging
Ambient
Background
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
Alternative Names
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Citation
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.5-1.5 ng/ml.
Activity
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