Recombinant Human Xaa-Pro Aminopeptidase P3/XPNPEP3 (N, C-6His)
Recombinant Human Aminopeptidase P3 is produced by our E.coli expression system and the target gene encoding Met1-Ser507 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus. Bon Opus Cat. #CE92
BackgroundProbable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.
ALTnamesProbable Xaa-Pro Aminopeptidase 3, X-Pro Aminopeptidase 3, Aminopeptidase P3, APP3, XPNPEP3