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Recombinant Human Vascular Eendothelial Growth Factor B/VEGFB (N-Fc)

Recombinant Human Vascular Eendothelial Growth Factor B/VEGFB (N-Fc)

SKU: CS78-10ug
$110.00Price
Recombinant Human Vascular Endothelial Growth Factor B is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus. Bon Opus Cat. #CS78
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P49765
Species
Human
Expression System
Human Cells
Target Sequence
Pro22-Ala207
Tag
N-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Vascular endothelial growth factor B;VEGF-B;VEGF-related factor;VRF
Alternative Names
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Citation
NA
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