Recombinant Human V-Set and Transmembrane Domain-Containing 1/VSTM1 (C-6His)
Recombinant Human VSTM1 is produced by our Mammalian expression system and the target gene encoding Tyr17-Thr135 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CJ71
BackgroundV-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesV-set and transmembrane domain-containing protein 1,SIRL-1,Signal inhibitory receptor on leukocytes-1,VSTM1