Recombinant Human uPAR (C-His)
Recombinant Human Urokinase Plasminogen Activator Surface Receptor is produced by our Mammalian expression system and the target gene encoding Leu23-Arg303 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #BP121
ExpressionHuman 293 Cells
FormulationLyophilized from a 0.2 um filtered solution of PBS, pH 7.4
BackgroundUrokinase plasminogen activator surface receptor (uPAR) is a receptor protein for urokinase plasminogen activator (uPA) and pro-uPA. It is expressed by T-cells, NK cells, monocytes, and neutrophils as well as non-hematopoietic cells that include vascular endothelial cells, fibroblasts, smooth muscle cells, keratinocytes, placental trophoblasts, hepatocytes, and a wide variety of tumor cells (including breast, colon, and prostate carcinoma, melanoma). It plays an important role in localizing and promoting plasmin formation. uPAR is also involved in multiple biological processes including angiogenesis, monocyte migration, cancer metastasis, trophoblast implantation, and wound healing.
ALTnamesUrokinase Plasminogen Activator Surface Receptor; U-PAR; uPAR; Monocyte activation antigen Mo3; CD87; PLAUR; MO3; UPAR