Recombinant Human Ubiquitin-Conjugating Enzyme E2 B is produced by our E.coli expression system and the target gene encoding Met1-Ser152 is expressed. Bon Opus Cat. #BP022
Recombinant Human UBE2B/HR6B
SKU: BP022-50ug
$331.00Price
top of page
[{"key":"BP022-500ug","value":"Backorder"},{"key":"BP022-10ug","value":"Backorder"},{"key":"BP022-50ug","value":"Backorder"}]
Contact Us
Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P63146
Species
Human
Expression System
E.coli
Target Sequence
Met1-Ser152
Tag
tag free
Formulation
Supplied as a 0.2 um filtered solution of 10mM HEPES, pH 7.5
Packaging
Dry ice/ice pack
Background
Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B can be found in the nucleus and cytoplasm and is highly expressed in the brain, heart, and testis. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins, and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth. Moreover, UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia. UBE2B is overexpressed in mouse and human breast cancer cell lines and tumors and has been reported to provide resistance to chemotherapy drugs.
Purity
greater than 95% as determined by reducing SDS-PAGE.
Ubiquitin-Conjugating Enzyme E2 B; RAD6 Homolog B; HR6B; hHR6B; Ubiquitin Carrier Protein B;Ubiquitin-Conjugating Enzyme E2-17 kDa; Ubiquitin-Protein Ligase B; UBE2B; RAD6B
Alternative Names
Be the first to submit a citation to get publication rewards
Citation
NA
Activity
bottom of page