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Recombinant Human TWEAK Receptor/TWEAK R/TNFRSF12A (C-Fc)

SKU: CX27-10ug
$95.00Price
Recombinant Human TWEAK Receptor is produced by our Mammalian expression system and the target gene encoding Glu28-Trp79 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CX27
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  • Accession Number

    Q9NP84

  • Background

    Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.

  • Expression

    Human Cells

  • Packaging

    Ambient

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

  • ALTnames

    TNFRSF12A,Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor.