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Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (C-6His)

SKU: CI39-10ug
$105.00Price
Recombinant Human Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI39
Size
  • Accession Number

    P20333
  • Background

    Tumor necrosis factor receptor superfamily member 1B is a 461 amino acids protein that belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
  • Expression

    Human Cells
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
  • ALTnames

    Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor type II,p75,p80 TNF-alpha receptor,TBP-2,TBPII,TNFRSF1B,TNFBR, TNFR2