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Recombinant Human Tumor Necrosis Factor Receptor I/TNFRSF1A/CD120a (C-Fc)

SKU: CP04-10ug
$95.00Price
Recombinant Human Tumor Necrosis Factor Receptor I is produced by our Mammalian expression system and the target gene encoding Leu30-Thr211 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CP04
Size
  • Accession Number

    P19438
  • Background

    Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) is a member of the tumor necrosis factor receptor superfamily. TNFRSF1A is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome.
  • Expression

    Human Cells
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
  • ALTnames

    Tumor necrosis factor receptor superfamily member 1A,TNFRSF1A,Tumor necrosis factor receptor 1, TNF-R1, TNF-RI, p55, p60, CD120a, TNFAR, TNFR1