Recombinant Human Tryptophan--tRNA Ligase, Cytoplasmic/WARS/TrpRS (N-6His)
Recombinant Human TrpRS is produced by our E.coli expression system and the target gene encoding Met1-Gln471 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #C300
BackgroundThere exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
ALTnamesWARS also known as Tryptophanyl-tRNA synthetase, Interferon-induced protein 53.