Recombinant Human Tryptase epsilon/Brain-Specific Protease 4/BSSP-4 (C-6His)

Recombinant Human Tryptase epsilon/Brain-Specific Protease 4/BSSP-4 (C-6His)

SKU: C383-10ug
Recombinant Human Tryptase epsilon is produced by our Mammalian expression system and the target gene encoding Ala33-Ser317 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C383
  • Accession Number

  • Background

    Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, α1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
  • Expression

    Human Cells
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, 10% Glycerol, pH 4.5.
  • ALTnames

    Brain-Specific Serine Protease 4, BSSP-4, Serine Protease 22, Serine Protease 26, Tryptase Epsilon, PRSS22, BSSP4, PRSS26

(800) 943-6396

150 Essex St, Millburn, NJ 07041, USA

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