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Recombinant Human Troponin C/TN-C/TNNC1(N-6His)
Recombinant Human slow skeletal and cardiac muscles is produced by our E.coli expression system and the target gene encoding Met1-Glu161 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CR51

Recombinant Human Troponin C/TN-C/TNNC1(N-6His)

SKU: CR51-10ug
$95.00Price
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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

Please contact us to order for  international shipments.

Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P63316
Species
Human
Expression System
E.coli
Target Sequence
Met1-Glu161
Tag
N-His
Formulation
Supplied as a 0.2 um filtered solution of 20mM Tris,100mM NaCl,1mM DTT,10% Glycerol,pH 8.0.
Packaging
Dry ice/Polar packs
Background
Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93% amino acid sequence identity with mouse and rat cardiac Troponin I.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
CMH7; TNNC1; TNNI3; Troponin I
Alternative Names
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Citation
NA
Activity
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