Recombinant Human Triggering receptor expressed on myeloid cells 2 is produced by our Mammalian expression system and the target gene encoding His19-Ser174 is expressed with a human IgG1 Fc tag at the C-terminus.

Recombinant Human TREM2 (C-Fc)

Name: Recombinant Human TREM2 (C-Fc)
SKU: C15X-10ug

SKU: C15X-10ug

$79.00

Size

Quantity

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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 EU/ug

Accession Number

Q9NZC2

Species

Human

Expression System

Human Cells

Target Sequence

His19-Ser174

C-Fc

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Packaging

Ambient

Background

TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes regulated intramembrane proteolysis (RIP). TREM2 is preferentially expressed in microglia and is functionally required for migration, cytokine release, phagocytosis, lipid sensing, ApoE binding, shielding of amyloid plaques, and microglia proliferation in the brian. Most of the functionally investigated mutations are located within the Ig-like domain of TREM2