Recombinant Human Transcription Initiation Factor IIB/TFIIB/GTF2B (N-GST)
Recombinant Human Transcription Initiation Factor IIB is produced by our E.coli expression system and the target gene encoding Met1-Leu316 is expressed with a GST tag at the N-terminus. Bon Opus Cat. #C293
BackgroundTranscription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. TFIIB plays a role as a bridge between IID, which initially recognizes the promoter sequence, and RNA polymerase II. TFIIB is involved in the selection of transcription start site.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, pH 8.0.
ALTnamesTranscription Initiation Factor IIB, General Transcription Factor TFIIB, S300-II, GTF2B, TF2B, TFIIB