Recombinant Human Tissue Inhibitor of Metalloproteinases 4/TIMP-4 (C-6His)
Recombinant Human Tissue Inhibitor of Metalloproteinases 4 is produced by our Mammalian expression system and the target gene encoding Cys30-Pro224 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CJ60
BackgroundMetalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
ALTnamesMetalloproteinase inhibitor 4,TIMP-4,Tissue inhibitor of metalloproteinases 4,TIMP4