BackgroundTIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is one newly discovered immune receptor on some percentage of T cells and Natural Killer Cells(NK). It is also identified as WUCAM and Vstm3. TIGIT could bind to CD155(PVR) on dendritic cells(DCs), macrophages, etc. with high affinity, and also to CD112(PVRL2) with lower affinity.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesT-cell immunoreceptor with Ig and ITIM domains,,VSIG9, VSTM3,TIGIT,V-set and transmembrane domain-containing protein 3,V-set and immunoglobulin domain-containing protein 9