Recombinant Human Thioredoxin-2/TXN2 (N-6His)
Recombinant Human Thioredoxin-2 is produced by our E.coli expression system and the target gene encoding Thr60-Gly166 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #C182
BackgroundThioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
ALTnamesThioredoxin Mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2