Our first tau protein expressed in mammalian cells. It has the closest modification and folding as in mammalian brains. Activity is verified by multiple users.

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Recombinant Human Tau Protein (Mammalian expressed, Active)

Name: Recombinant Human Tau Protein (Mammalian expressed, Active)
SKU: BP228-10ug

SKU: BP228-10ug

$110.00

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Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P10636-8

Species

Human

Expression System

Human 293 Cells

Target Sequence

Ala2-Leu441

N-His

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Packaging

Ambient

Background

Tau is a microtubule-associated protein expressed primarily in neurons. Tau promotes the assembly and stabilization of microtubules along with other MAP proteins. It is thought that other proteins can compensate for loss of Tau protein function as Tau knockout mice are viable and show no signs of neurodegeneration. There are multiple isoforms of Tau created by alternative splicing of exons 2, 3, and 10. When tau proteins are defective and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.