Recombinant Human Sulfotransferase 1A1/SULT1A1 (N-6His)
Recombinant Human Sulfotransferase 1A1 is produced by our E.coli expression system and the target gene encoding Met1-Leu295 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CF97
BackgroundSulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver, lung, adrenal, brain, platelets, and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,1mM EDTA,pH 8.0.
ALTnamesSulfotransferase 1A1, ST1A1, Aryl sulfotransferase 1, HAST1/HAST2, Phenol Sulfotransferase 1, Phenol-Sulfating Phenol Sulfotransferase 1, P-PST 1, ST1A3, Thermostable Phenol Sulfotransferase, Ts-PST, SULT1A1, STP, STP1, OK/SW-cl.88