Recombinant Human Sorbitol Dehydrogenase/SORD (C-6His)

Recombinant Human Sorbitol Dehydrogenase/SORD (C-6His)

SKU: C885-10ug
Recombinant Human Sorbitol Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Pro357 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C885
  • Accession Number

  • Background

    Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.
  • Expression

    Human Cells
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,0.2M NaCl,5mM DTT,20% glycerol,pH8.0.
  • ALTnames

    Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD

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