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Recombinant Human STAT1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed. Bon Opus Cat. #CF22

Recombinant Human Signal Transducer and Activator of Transcription 1/STAT1

SKU: CF22-10ug
$110.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P42224
Species
Human
Expression System
E.coli
Target Sequence
Met1-Val712
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Signal Transducer and Activator of Transcription 1-Alpha/Beta; Transcription Factor ISGF-3 Components p91/p84; STAT1
Alternative Names
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Citation
NA
Activity
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