Recombinant Human Semaphorin-3A/SEMA3A (N-6His-Flag)
Recombinant Human Semaphorin 3A is produced by our Mammalian expression system and the target gene encoding Lys26-Phe546 is expressed with a 6His-Flag tag at the C-terminus. Bon Opus Cat. #CP98
Backgroundemaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnamesSynonyms: Semaphorin III; SEMA3A; SEMAD; Hsema-I; SEMA1; SemD; Semad; coll-1 ; Hsema-III; Sema III