Recombinant Human Repulsive guidance molecule A is produced by our E.coli expression system and the target gene encoding Pro169-Gly422 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CH40

Recombinant Human Repulsive Guidance Molecule A/RGMA (N-6His)

Name: Recombinant Human Repulsive Guidance Molecule A/RGMA (N-6His)
SKU: CH40-10ug

SKU: CH40-10ug

$100.00

Quantity

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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

AAI51133.1

Species

Human

Expression System

E.coli

Target Sequence

Pro169-Gly422

N-His

Formulation

Supplied as a 0.2 um filtered solution of 20mM Tris-HCl.1mMDTT,150mMNacl,1mMEDTA,pH8.0.

Packaging

Dry ice/Polar packs

Background

Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.