Recombinant Human Protein Disulfide-Isomerase A3/PDIA3 (C-6His)
SKU: CC92-10ug
$150.00Price
Recombinant Human Protein Disulfide-Isomerase A3 is produced by our Mammalian expression system and the target gene encoding Ser25-Leu505 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CC92
Size
Accession Number
A5D7E8Background
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.Expression
Human CellsPackaging
Dry ice/Polar packsFormulation
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5.ALTnames
PDIA3 protein,Protein disulfide-isomerase A3,58 kDa glucose-regulated protein,Disulfide isomerase ER-60,ER protein 57