Recombinant Human Proenkephalin-B/PDYN(C-6His)
Recombinant Human Proenkephalin-B is produced by our Mammalian expression system and the target gene encoding Asp21-Ala254 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C812
BackgroundProenkephalin-B(PDYN), belongs to the opioid neuropeptide precursor family. The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Leu-enkephalins, which is a type of Proenkephalin-B, compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesADCA; PENKB; SCA23; PDYN; Dynorphin B; Big Dyn