Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C945

Recombinant Human Porphobilinogen Deaminase/HMBS/PBGD (C-6His)

Name: Recombinant Human Porphobilinogen Deaminase/HMBS/PBGD (C-6His)
SKU: C945-10ug

SKU: C945-10ug

$158.00

Size

Quantity

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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P08397

Species

Human

Expression System

Human Cells

Target Sequence

Ser2-His361

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Packaging

Ambient

Background

Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.