Recombinant Human Phosphomevalonate Kinase/PMVK (N-6His)

Recombinant Human Phosphomevalonate Kinase/PMVK (N-6His)

SKU: C248-10ug
Recombinant Human Phosphomevalonate Kinase is produced by our E.coli expression system and the targetgene encoding Met1-Leu192 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #C248
  • Accession Number

  • Background

    Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
  • Expression

    E. coli
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.
  • ALTnames

    Phosphomevalonate Kinase, PMKase, hPMK, PMVK, PMKI
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