Recombinant Human Neuronal Pentraxin-1 is produced by our Mammalian expression system and the target gene encoding Gln23-Asn432 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CU54

Recombinant Human Neuronal Pentraxin-1/NPTX1 (C-6His)

Name: Recombinant Human Neuronal Pentraxin-1/NPTX1 (C-6His)
SKU: CU54-10ug
Price: 95 USD
Availability: InStock

SKU: CU54-10ug

$95.00

Size

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

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Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

Q15818

Species

Human

Expression System

Human Cells

Target Sequence

Gln23-Asn432

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of PBS, 1mM EDTA, pH 7.4.

Packaging

Ambient

Background

Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97% aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it forms complexes with NPTXR. It may be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.