Recombinant Human NCR3 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr138 is expressed with a Fc tag at the C-terminus.
Recombinant Human NCR3/NKp30/CD337 (C-Fc)
SKU: CG15-10ug
$158.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O14931
Species
Human
Expression System
Human Cells
Target Sequence
Leu19-Thr138
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
Packaging
Ambient
Background
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Natural Cytotoxicity Triggering Receptor 3; Activating Natural Killer Receptor p30; Natural Killer Cell p30-Related Protein; NK-p30; NKp30; CD337; NCR3; 1C7; LY117
Alternative Names
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Citation
NA
Activity
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