Recombinant Human Myc-Associated Factor X/MAX (C-6His)
Recombinant Human Myc-Associated Factor X is produced by our E.coli expression system and the target gene encoding Met1-Ser151 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C196
BackgroundMyc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. It may repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 50mM Imidazole, 250mM NaCl, pH 8.5.
ALTnamesProtein Max, Class D Basic Helix-Loop-Helix Protein 4, bHLHd4,, Myc-Associated Factor X, MAX, BHLHD4