Recombinant Human Mitochondrial Fission 1 Protein/FIS1 (C-6His)

Recombinant Human Mitochondrial Fission 1 Protein/FIS1 (C-6His)

SKU: CF28-10ug
Recombinant Human Mitochondrial Fission 1 Protein is produced by our E.coli expression system and the target gene encoding Met1-Gly122 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CF28
  • Accession Number

  • Background

    Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • Expression

    E. coli
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM Tris, pH 8.0.
  • ALTnames

    Mitochondrial Fission 1 Protein, FIS1 Homolog, hFis1, Tetratricopeptide Repeat Protein 11, TPR Repeat Protein 11, FIS1, TTC11, CGI-135
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