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Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CA37

Recombinant Human Lysosomal Pro-X Carboxypeptidase/PRCP (C-6His)

SKU: CA37-10ug
$158.00Price
Quantity
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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P42785
Species
Human
Expression System
Human Cells
Target Sequence
Leu22-His496
Tag
C-His
Formulation
Supplied as a 0.2 um filtered solution of 20mM NaAc-HAc, 150mM NaCl, 10% Glycerol, pH4.5.
Packaging
Dry ice/Polar packs
Background
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Lysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP
Alternative Names
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Citation
NA
Activity
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