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Recombinant Human Lymphocyte Function-associated Antigen 3/CD58/LFA-3 (C-Fc)
Recombinant Human Lymphocyte function-associated antigen 3 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus.

Recombinant Human Lymphocyte Function-associated Antigen 3/CD58/LFA-3 (C-Fc)

SKU: CB46-10ug
$95.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
AAH05930
Species
Human
Expression System
Human Cells
Target Sequence
Phe29-Arg215
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; CD58; LFA3;Ag3; CD58 antigen
Alternative Names
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Citation
NA
Activity
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