BackgroundLeukocyte Immunoglobulin-Like Receptor Subfamily A Member 2 (LILRA2) is a single-pass type I membrane protein. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 contains four Ig-like C2-type domains, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. LILRA2 does not bind class I MHC antigens.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnamesLeukocyte Immunoglobulin-Like Receptor Subfamily A Member 2, CD85 Antigen-Like Family Member H, Immunoglobulin-Like Transcript 1, ILT-1, Leukocyte Immunoglobulin-Like Receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7